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Matrine induces caspase-independent program cell death in hepatocellular carcinoma through bid-mediated nuclear translocation of apoptosis inducing factor
Matrine, a clinical drug in China, has been used to treat viral hepatitis, cardiac arrhythmia and skin inflammations. Matrine also exhibits chemotherapeutic potential through its ability to trigger cancer cell death. However, the mechanisms involved are still largely unknown. The objective of this s...
Autores principales: | Zhou, Huan, Xu, Minying, Gao, Ya, Deng, Zhigang, Cao, Hanwei, Zhang, Wenqing, Wang, Qiao, Zhang, Bing, Song, Gang, Zhan, Yanyan, Hu, Tianhui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007561/ https://www.ncbi.nlm.nih.gov/pubmed/24628719 http://dx.doi.org/10.1186/1476-4598-13-59 |
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