Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells

BACKGROUND: The full-length membrane protein tyrosine kinase 7 (PTK7) pseudokinase, an important component of the planar cell polarity and the Wnt canonical and non-canonical pathways, is a subject of step-wise proteolysis in cells and tissues. The proteolysis of PTK7 involves membrane type-matrix m...

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Detalles Bibliográficos
Autores principales: Golubkov, Vladislav S, Strongin, Alex Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007575/
https://www.ncbi.nlm.nih.gov/pubmed/24618420
http://dx.doi.org/10.1186/1478-811X-12-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007575/
https://www.ncbi.nlm.nih.gov/pubmed/24618420
http://dx.doi.org/10.1186/1478-811X-12-15

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