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Comparative analysis of resistant and susceptible macrophage gene expression response to Leishmania major parasite

BACKGROUND: Leishmania are obligated intracellular pathogens that replicate almost exclusively in macrophages. The outcome of infection depends largely on parasite pathogenicity and virulence but also on the activation status and genetic background of macrophages. Animal models are essential for a b...

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Detalles Bibliográficos
Autores principales: Rabhi, Imen, Rabhi, Sameh, Ben-Othman, Rym, Aniba, Mohamed Radhouane, Trentin, Bernadette, Piquemal, David, Regnault, Béatrice, Guizani-Tabbane, Lamia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007596/
https://www.ncbi.nlm.nih.gov/pubmed/24148319
http://dx.doi.org/10.1186/1471-2164-14-723