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Atypical protein kinase C couples cell sorting with primitive endoderm maturation in the mouse blastocyst

During mouse pre-implantation development, extra-embryonic primitive endoderm (PrE) and pluripotent epiblast precursors are specified in the inner cell mass (ICM) of the early blastocyst in a ‘salt and pepper’ manner, and are subsequently sorted into two distinct layers. Positional cues provided by...

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Detalles Bibliográficos
Autores principales: Saiz, Néstor, Grabarek, Joanna B., Sabherwal, Nitin, Papalopulu, Nancy, Plusa, Berenika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007710/
https://www.ncbi.nlm.nih.gov/pubmed/24067354
http://dx.doi.org/10.1242/dev.093922