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IL-12 and IL-27 regulate the phagolysosomal pathway in mycobacteria-infected human macrophages

BACKGROUND: The cytokine environment at the site of infection is important to the control of mycobacteria by host macrophages. During chronic infection immunosuppressive cytokines are likely to favor mycobacterial growth, persistence, and an avoidance of proper antigen processing and presentation. T...

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Detalles Bibliográficos
Autores principales: Jung, Joo-Yong, Robinson, Cory M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007735/
https://www.ncbi.nlm.nih.gov/pubmed/24618498
http://dx.doi.org/10.1186/1478-811X-12-16