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The molecular basis for selective assembly of the UBAP1-containing endosome-specific ESCRT-I complex

ESCRT-I is essential for the multivesicular body (MVB) sorting of ubiquitylated cargo such as epidermal growth factor receptor, as well as for several cellular functions, such as cell division and retroviral budding. ESCRT-I has four subunits; TSG101, VPS28, VPS37 and MVB12. There are several member...

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Detalles Bibliográficos
Autores principales: Wunderley, Lydia, Brownhill, Kim, Stefani, Flavia, Tabernero, Lydia, Woodman, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007767/
https://www.ncbi.nlm.nih.gov/pubmed/24284069
http://dx.doi.org/10.1242/jcs.140673