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Gold (I) N-heterocyclic carbene complex inhibits mouse melanoma growth by p53 upregulation
BACKGROUND: Cancer treatment using gold (I) complexes is becoming popular. In this study, a gold (I) N-heterocyclic complex designated as complex 3 was synthesized, its cytotoxicity was examined, and its anti-melanoma activity was evaluated in vitro and in vivo. METHODS: Viability of cancer cells wa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007776/ https://www.ncbi.nlm.nih.gov/pubmed/24625085 http://dx.doi.org/10.1186/1476-4598-13-57 |