Gold (I) N-heterocyclic carbene complex inhibits mouse melanoma growth by p53 upregulation

BACKGROUND: Cancer treatment using gold (I) complexes is becoming popular. In this study, a gold (I) N-heterocyclic complex designated as complex 3 was synthesized, its cytotoxicity was examined, and its anti-melanoma activity was evaluated in vitro and in vivo. METHODS: Viability of cancer cells wa...

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Detalles Bibliográficos
Autores principales: Nandy, Abhishek, Dey, Sumit Kumar, Das, Sujata, Munda, Rudra Narayan, Dinda, Joydev, Saha, Krishna Das
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007776/
https://www.ncbi.nlm.nih.gov/pubmed/24625085
http://dx.doi.org/10.1186/1476-4598-13-57

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