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Autophagy protects against human islet amyloid polypeptide‐associated apoptosis
Aims/Introduction: Islets in type 2 diabetes are characterized by deposition of islet amyloid polypeptide (IAPP) as well as β‐cell dysfunction. The unique amyloidogenic character of human (h)IAPP is associated with cytotoxicity. Autophagy is a ubiquitous system of cellular recycling that contribute...
Autores principales: | Morita, Shuhei, Sakagashira, Setsuya, Shimajiri, Yoshinori, Eberhardt, Norman L, Kondo, Toshikazu, Kondo, Tomoyoshi, Sanke, Tokio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008015/ https://www.ncbi.nlm.nih.gov/pubmed/24843461 http://dx.doi.org/10.1111/j.2040-1124.2010.00065.x |
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