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A distinct group of CpG islands shows differential DNA methylation between replicas of the same cell line in vitro

BACKGROUND: CpG dinucleotide-rich genomic DNA regions, known as CpG islands (CGIs), can be methylated at their cytosine residues as an epigenetic mark that is stably inherited during cell mitosis. Differentially methylated regions (DMRs) are genomic regions showing different degrees of DNA methylati...

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Detalles Bibliográficos
Autores principales: Cocozza, Sergio, Scala, Giovanni, Miele, Gennaro, Castaldo, Imma, Monticelli, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008136/
https://www.ncbi.nlm.nih.gov/pubmed/24106769
http://dx.doi.org/10.1186/1471-2164-14-692