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A distinct group of CpG islands shows differential DNA methylation between replicas of the same cell line in vitro
BACKGROUND: CpG dinucleotide-rich genomic DNA regions, known as CpG islands (CGIs), can be methylated at their cytosine residues as an epigenetic mark that is stably inherited during cell mitosis. Differentially methylated regions (DMRs) are genomic regions showing different degrees of DNA methylati...
Autores principales: | Cocozza, Sergio, Scala, Giovanni, Miele, Gennaro, Castaldo, Imma, Monticelli, Antonella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008136/ https://www.ncbi.nlm.nih.gov/pubmed/24106769 http://dx.doi.org/10.1186/1471-2164-14-692 |
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