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A bioinformatics approach reveals novel interactions of the OVOL transcription factors in the regulation of epithelial – mesenchymal cell reprogramming and cancer progression

BACKGROUND: Mesenchymal to Epithelial Transition (MET) plasticity is critical to cancer progression, and we recently showed that the OVOL transcription factors (TFs) are critical regulators of MET. Results of that work also posed the hypothesis that the OVOLs impact MET in a range of cancers. We now...

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Detalles Bibliográficos
Autores principales: Roca, Hernan, Pande, Manjusha, Huo, Jeffrey S, Hernandez, James, Cavalcoli, James D, Pienta, Kenneth J, McEachin, Richard C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008156/
https://www.ncbi.nlm.nih.gov/pubmed/24612742
http://dx.doi.org/10.1186/1752-0509-8-29