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Rewiring of regenerated axons by combining treadmill training with semaphorin3A inhibition

BACKGROUND: Rats exhibit extremely limited motor function recovery after total transection of the spinal cord (SCT). We previously reported that SM-216289, a semaphorin3A inhibitor, enhanced axon regeneration and motor function recovery in SCT adult rats. However, these effects were limited because...

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Detalles Bibliográficos
Autores principales: Zhang, Liang, Kaneko, Shinjiro, Kikuchi, Kaoru, Sano, Akihiko, Maeda, Miho, Kishino, Akiyoshi, Shibata, Shinsuke, Mukaino, Masahiko, Toyama, Yoshiaki, Liu, Meigen, Kimura, Toru, Okano, Hideyuki, Nakamura, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008261/
https://www.ncbi.nlm.nih.gov/pubmed/24618249
http://dx.doi.org/10.1186/1756-6606-7-14