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Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts

BACKGROUND: Cellular senescence can be induced by a variety of extrinsic stimuli, and sustained exposure to sunlight is a key factor in photoaging of the skin. Accordingly, irradiation of skin fibroblasts by UVB light triggers cellular senescence, which is thought to contribute to extrinsic skin agi...

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Detalles Bibliográficos
Autores principales: Greussing, Ruth, Hackl, Matthias, Charoentong, Pornpimol, Pauck, Alexander, Monteforte, Rossella, Cavinato, Maria, Hofer, Edith, Scheideler, Marcel, Neuhaus, Michael, Micutkova, Lucia, Mueck, Christoph, Trajanoski, Zlatko, Grillari, Johannes, Jansen-Dürr, Pidder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008267/
https://www.ncbi.nlm.nih.gov/pubmed/23557329
http://dx.doi.org/10.1186/1471-2164-14-224