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Altering the intratumoral localization of macrophages to inhibit cancer progression
Hypoxia confers to macrophages angiogenic and immunosuppressive properties which promote tumor growth and progression. Preventing the migration of macrophages into hypoxic tumor regions hinders angiogenesis and restores the tumor-suppressive properties of these immune cells. We have recently uncover...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008455/ https://www.ncbi.nlm.nih.gov/pubmed/24800172 http://dx.doi.org/10.4161/onci.27872 |