Mouse Spermatocytes Express CYP2E1 and Respond to Acrylamide Exposure

Metabolism of xenobiotics by cytochrome P450s (encoded by the CYP genes) often leads to bio-activation, producing reactive metabolites that interfere with cellular processes and cause DNA damage. In the testes, DNA damage induced by xenobiotics has been associated with impaired spermatogenesis and a...

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Detalles Bibliográficos
Autores principales: Nixon, Belinda J., Katen, Aimee L., Stanger, Simone J., Schjenken, John E., Nixon, Brett, Roman, Shaun D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008485/
https://www.ncbi.nlm.nih.gov/pubmed/24788432
http://dx.doi.org/10.1371/journal.pone.0094904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008485/
https://www.ncbi.nlm.nih.gov/pubmed/24788432
http://dx.doi.org/10.1371/journal.pone.0094904

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