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Routes of Delivery for CpG and Anti-CD137 for the Treatment of Orthotopic Kidney Tumors in Mice

We have found previously that the tumor cell lines, Renca (a renal cancer) and MC38 (a colon tumor) which had been injected subcutaneously in mice, could be successfully treated with a combination therapy of an oligodeoxynucleotide (CpG1826) (injected intratumorally) and anti-CD137 antibody (injecte...

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Detalles Bibliográficos
Autores principales: Westwood, Jennifer A., Potdevin Hunnam, Titaina C. U., Pegram, Hollie J., Hicks, Rodney J., Darcy, Phillip K., Kershaw, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008493/
https://www.ncbi.nlm.nih.gov/pubmed/24788789
http://dx.doi.org/10.1371/journal.pone.0095847