Loss of Function of TET2 Cooperates with Constitutively Active KIT in Murine and Human Models of Mastocytosis

Systemic Mastocytosis (SM) is a clonal disease characterized by abnormal accumulation of mast cells in multiple organs. Clinical presentations of the disease vary widely from indolent to aggressive forms, and to the exceedingly rare mast cell leukemia. Current treatment of aggressive SM and mast cel...

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Detalles Bibliográficos
Autores principales: De Vita, Serena, Schneider, Rebekka K., Garcia, Michael, Wood, Jenna, Gavillet, Mathilde, Ebert, Benjamin L., Gerbaulet, Alexander, Roers, Axel, Levine, Ross L., Mullally, Ann, Williams, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008566/
https://www.ncbi.nlm.nih.gov/pubmed/24788138
http://dx.doi.org/10.1371/journal.pone.0096209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008566/
https://www.ncbi.nlm.nih.gov/pubmed/24788138
http://dx.doi.org/10.1371/journal.pone.0096209

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