CLN3 Deficient Cells Display Defects in the ARF1-Cdc42 Pathway and Actin-Dependent Events

Juvenile Batten disease (juvenile neuronal ceroid lipofuscinosis, JNCL) is a devastating neurodegenerative disease caused by mutations in CLN3, a protein of undefined function. Cell lines derived from patients or mice with CLN3 deficiency have impairments in actin-regulated processes such as endocyt...

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Detalles Bibliográficos
Autores principales: Schultz, Mark L., Tecedor, Luis, Stein, Colleen S., Stamnes, Mark A., Davidson, Beverly L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008583/
https://www.ncbi.nlm.nih.gov/pubmed/24792215
http://dx.doi.org/10.1371/journal.pone.0096647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008583/
https://www.ncbi.nlm.nih.gov/pubmed/24792215
http://dx.doi.org/10.1371/journal.pone.0096647

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