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Pancreatic Ductal Adenocarcinoma Contains an Effector and Regulatory Immune Cell Infiltrate that Is Altered by Multimodal Neoadjuvant Treatment

OBJECTIVE: The immune response to pancreatic ductal adenocarcinoma (PDA) may play a role in defining its uniquely aggressive biology; therefore, we sought to clearly define the adaptive immune infiltrate in PDA. DESIGN: We used immunohistochemistry and flow cytometry to characterize the immune infil...

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Detalles Bibliográficos
Autores principales: Shibuya, Kendall C., Goel, Vikas K., Xiong, Wei, Sham, Jonathan G., Pollack, Seth M., Leahy, Allison M., Whiting, Samuel H., Yeh, Matthew M., Yee, Cassian, Riddell, Stanley R., Pillarisetty, Venu G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008589/
https://www.ncbi.nlm.nih.gov/pubmed/24794217
http://dx.doi.org/10.1371/journal.pone.0096565