Cargando…
Vitamin D Up-Regulates the Vitamin D Receptor by Protecting It from Proteasomal Degradation in Human CD4(+) T Cells
The active form of vitamin D(3), 1,25(OH)(2)D(3), has significant immunomodulatory properties and is an important determinant in the differentiation of CD4(+) effector T cells. The biological actions of 1,25(OH)(2)D(3) are mediated by the vitamin D receptor (VDR) and are believed to correlate with t...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008591/ https://www.ncbi.nlm.nih.gov/pubmed/24792400 http://dx.doi.org/10.1371/journal.pone.0096695 |