Vitamin D Up-Regulates the Vitamin D Receptor by Protecting It from Proteasomal Degradation in Human CD4(+) T Cells

The active form of vitamin D(3), 1,25(OH)(2)D(3), has significant immunomodulatory properties and is an important determinant in the differentiation of CD4(+) effector T cells. The biological actions of 1,25(OH)(2)D(3) are mediated by the vitamin D receptor (VDR) and are believed to correlate with t...

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Detalles Bibliográficos
Autores principales: Kongsbak, Martin, von Essen, Marina R., Boding, Lasse, Levring, Trine B., Schjerling, Peter, Lauritsen, Jens P. H., Woetmann, Anders, Ødum, Niels, Bonefeld, Charlotte M., Geisler, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008591/
https://www.ncbi.nlm.nih.gov/pubmed/24792400
http://dx.doi.org/10.1371/journal.pone.0096695

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