Toll-Like Receptor (TLR)-1/2 Triggering of Multiple Myeloma Cells Modulates Their Adhesion to Bone Marrow Stromal Cells and Enhances Bortezomib-Induced Apoptosis

In multiple myeloma (MM), the malignant plasma cells usually localize to the bone marrow where they develop drug resistance due to adhesion to stromal cells and various environmental signals. Hence, modulation of this interaction is expected to influence drug sensitivity of MM cells. Toll-like recep...

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Detalles Bibliográficos
Autores principales: Abdi, Jahangir, Mutis, Tuna, Garssen, Johan, Redegeld, Frank A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008602/
https://www.ncbi.nlm.nih.gov/pubmed/24794258
http://dx.doi.org/10.1371/journal.pone.0096608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008602/
https://www.ncbi.nlm.nih.gov/pubmed/24794258
http://dx.doi.org/10.1371/journal.pone.0096608

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