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Alloisoleucine differentiates the branched-chain aminoacidemia of obese Zucker and diet-induced obesity (DIO) rats

OBJECTIVE: Circulating branched-chain amino acids (BCAAs) are elevated in obesity and this has been linked to obesity comorbidities. However it is unclear how obesity affects alloisoleucine, a BCAA and pathognomonic marker of branched-chain keto acid dehydrogenase complex (BCKDC) disorders. It has b...

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Detalles Bibliográficos
Autores principales: Olson, Kristine C., Chen, Gang, Xu, Yuping, Hajnal, Andras, Lynch, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008669/
https://www.ncbi.nlm.nih.gov/pubmed/24415721
http://dx.doi.org/10.1002/oby.20691