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Effects of a novel MC4R agonist on maintenance of reduced body weight in diet induced obese mice

OBJECTIVE: The physiology of the weight reduced (WR) state suggests that pharmacologic agents affecting energy homeostasis may have greater efficacy in WR individuals. Our aim was to establish a protocol that allows for evaluation of efficacy of weight maintenance agents and to assess the effectiven...

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Detalles Bibliográficos
Autores principales: Skowronski, Alicja A., Morabito, Michael V., Mueller, Bridget R., Lee, Samuel, Hjorth, Stephan, Lehmann, Anders, Watanabe, Kazuhisa, Zeltser, Lori M., Ravussin, Yann, Rosenbaum, Michael, LeDuc, Charles A., Leibel, Rudolph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008720/
https://www.ncbi.nlm.nih.gov/pubmed/24318934
http://dx.doi.org/10.1002/oby.20678