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Exploiting the power of LINE-1 retrotransposon mutagenesis for identification of genes involved in embryonic stem cell differentiation

Identifying the genes or epigenetic factors that control the self-renewal and differentiation of stem cells is critical to understanding the molecular basis of cell commitment. Although a number of insertional mutagenesis vectors have been developed for identifying gene functions in animal models, t...

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Detalles Bibliográficos
Autores principales: Lenka, Nibedita, Krishnan, Shruthi, Board, Philip, Rangasamy, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008784/
https://www.ncbi.nlm.nih.gov/pubmed/24610122
http://dx.doi.org/10.1007/s12015-014-9500-9