Cargo binding to Atg19 unmasks further Atg8 binding sites to mediate membrane-cargo apposition during selective autophagy

Autophagy protects cells from harmful substances such as protein aggregates, damaged mitochondria and intracellular pathogens and has been implicated in a variety of diseases. Selectivity of autophagic processes is mediated by cargo receptors that link cargo to Atg8 family proteins on the developing...

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Detalles Bibliográficos
Autores principales: Sawa-Makarska, Justyna, Abert, Christine, Romanov, Julia, Zens, Bettina, Ibiricu, Iosune, Martens, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009068/
https://www.ncbi.nlm.nih.gov/pubmed/24705553
http://dx.doi.org/10.1038/ncb2935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009068/
https://www.ncbi.nlm.nih.gov/pubmed/24705553
http://dx.doi.org/10.1038/ncb2935

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