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Cargo binding to Atg19 unmasks further Atg8 binding sites to mediate membrane-cargo apposition during selective autophagy
Autophagy protects cells from harmful substances such as protein aggregates, damaged mitochondria and intracellular pathogens and has been implicated in a variety of diseases. Selectivity of autophagic processes is mediated by cargo receptors that link cargo to Atg8 family proteins on the developing...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009068/ https://www.ncbi.nlm.nih.gov/pubmed/24705553 http://dx.doi.org/10.1038/ncb2935 |