Computational Survey of FHIT, A Putative Human Tumor Suppressor, Truncates Structure

BACKGROUND: Fragile Histidine Triad protein (FHIT), as a known tumor suppressor protein, has been proposed to play crucial role in inhibiting p53 degradation by MDM2. Studies have confirmed FHIT interaction with p53 or MDM2, although functional interacting domains of FHIT with MDM2 and/or p53 are no...

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Detalles Bibliográficos
Autores principales: Eslamparast, Ameneh, Ghahremani, Mohammad Hossein, Sardari, Soroush
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009097/
https://www.ncbi.nlm.nih.gov/pubmed/24834308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009097/
https://www.ncbi.nlm.nih.gov/pubmed/24834308

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