An In silico Based Comparison of Drug Interactions in Wild and Mutant Human β-tubulin through Docking Studies

BACKGROUND: Tubulin protein being the fundamental unit of microtubules is actively involved in cell division thus making them a potential anti-cancer drug target. In spite of many reported drugs against tubulin, few of them have started developing resistance in human β-tubulin due to amino acid subs...

Descripción completa

Detalles Bibliográficos
Autores principales: Chellasamy, Selvaakumar, Mohammed, Sudheer M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009099/
https://www.ncbi.nlm.nih.gov/pubmed/24834310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009099/
https://www.ncbi.nlm.nih.gov/pubmed/24834310

Ejemplares similares