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The Effect of tert-Butyl Hydroperoxide-Induced Oxidative Stress on Lean and Steatotic Rat Hepatocytes In Vitro

Oxidative stress and mitochondrial dysfunction play an important role in the pathogenesis of nonalcoholic fatty liver disease and toxic liver injury. The present study was designed to evaluate the effect of exogenous inducer of oxidative stress (tert-butyl hydroperoxide, tBHP) on nonfatty and steato...

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Detalles Bibliográficos
Autores principales: Kučera, Otto, Endlicher, René, Roušar, Tomáš, Lotková, Halka, Garnol, Tomáš, Drahota, Zdeněk, Červinková, Zuzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009166/
https://www.ncbi.nlm.nih.gov/pubmed/24847414
http://dx.doi.org/10.1155/2014/752506