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Beneficial Effect of Glucose Control on Atherosclerosis Progression in Diabetic ApoE(−/−) Mice: Shown by Rage Directed Imaging

Objective. Receptor for advanced glycated endproducts (RAGE) plays an important role in atherogenesis in diabetes. We imaged RAGE to investigate the effect of glucose control to suppress RAGE and reduce atherosclerosis in apolipoprotein E null (apoE(−/−)) diabetic mice. Methods and Results. Thirty-t...

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Detalles Bibliográficos
Autores principales: Tekabe, Yared, Kollaros, Maria, Li, Qing, Zhang, Geping, Li, Chong, Schmidt, Ann Marie, Johnson, Lynne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009322/
https://www.ncbi.nlm.nih.gov/pubmed/24829796
http://dx.doi.org/10.1155/2014/695391