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Downregulation of Bcl-2 Expression by miR-34a Mediates Palmitate-Induced Min6 Cells Apoptosis

Recent studies have demonstrated that the expression of miR-34a is significantly upregulated and associated with cell apoptosis in pancreatic β-cell treated with palmitate. Nevertheless, the underlying detailed mechanism is largely unknown. Here, we showed that miR-34a was significantly induced in M...

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Detalles Bibliográficos
Autores principales: Lin, Xiaojie, Guan, Hongyu, Huang, Zhimin, Liu, Juan, Li, Hai, Wei, Guohong, Cao, Xiaopei, Li, Yanbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009326/
https://www.ncbi.nlm.nih.gov/pubmed/24829923
http://dx.doi.org/10.1155/2014/258695