TMPRSS2-ERG Gene Fusions induce prostate tumorigenesis through modulating microRNA miR-200c

Chromosomal translocations that juxtapose the androgen-sensitive TMPRSS2 gene promoter to the oncogenic ETS-family transcription factor ERG result in excessive ERG overexpression in approximately 50% of prostate cancer (PCa) patients. Although numerous studies have investigated ERG-downstream genes,...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Jung, Wu, Longtao, Zhao, Jonathan C., Jin, Hong-Jian, Yu, Jindan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009393/
https://www.ncbi.nlm.nih.gov/pubmed/24186205
http://dx.doi.org/10.1038/onc.2013.461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009393/
https://www.ncbi.nlm.nih.gov/pubmed/24186205
http://dx.doi.org/10.1038/onc.2013.461

Ejemplares similares