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TMPRSS2-ERG Gene Fusions induce prostate tumorigenesis through modulating microRNA miR-200c
Chromosomal translocations that juxtapose the androgen-sensitive TMPRSS2 gene promoter to the oncogenic ETS-family transcription factor ERG result in excessive ERG overexpression in approximately 50% of prostate cancer (PCa) patients. Although numerous studies have investigated ERG-downstream genes,...
Autores principales: | Kim, Jung, Wu, Longtao, Zhao, Jonathan C., Jin, Hong-Jian, Yu, Jindan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009393/ https://www.ncbi.nlm.nih.gov/pubmed/24186205 http://dx.doi.org/10.1038/onc.2013.461 |
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