Hepcidin antagonists for potential treatments of disorders with hepcidin excess

The discovery of hepcidin clarified the basic mechanism of the control of systemic iron homeostasis. Hepcidin is mainly produced by the liver as a propeptide and processed by furin into the mature active peptide. Hepcidin binds ferroportin, the only cellular iron exporter, causing the internalizatio...

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Detalles Bibliográficos
Autores principales: Poli, Maura, Asperti, Michela, Ruzzenenti, Paola, Regoni, Maria, Arosio, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009444/
https://www.ncbi.nlm.nih.gov/pubmed/24808863
http://dx.doi.org/10.3389/fphar.2014.00086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009444/
https://www.ncbi.nlm.nih.gov/pubmed/24808863
http://dx.doi.org/10.3389/fphar.2014.00086

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