Tissue-Resident Exhausted Effector Memory CD8(+) T Cells Accumulate in the Retina during Chronic Experimental Autoimmune Uveoretinitis

Experimental autoimmune uveoretinitis is a model for noninfectious posterior segment intraocular inflammation in humans. Although this disease is CD4(+) T cell dependent, in the persistent phase of disease CD8(+) T cells accumulate. We show that these are effector memory CD8(+) T cells that differ f...

Descripción completa

Detalles Bibliográficos
Autores principales: Boldison, Joanne, Chu, Colin J., Copland, David A., Lait, Philippa J. P., Khera, Tarnjit K., Dick, Andrew D., Nicholson, Lindsay B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2014
Materias:
Autoimmunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009498/
https://www.ncbi.nlm.nih.gov/pubmed/24740509
http://dx.doi.org/10.4049/jimmunol.1301390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009498/
https://www.ncbi.nlm.nih.gov/pubmed/24740509
http://dx.doi.org/10.4049/jimmunol.1301390

Ejemplares similares