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Tissue-Resident Exhausted Effector Memory CD8(+) T Cells Accumulate in the Retina during Chronic Experimental Autoimmune Uveoretinitis

Experimental autoimmune uveoretinitis is a model for noninfectious posterior segment intraocular inflammation in humans. Although this disease is CD4(+) T cell dependent, in the persistent phase of disease CD8(+) T cells accumulate. We show that these are effector memory CD8(+) T cells that differ f...

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Detalles Bibliográficos
Autores principales:	Boldison, Joanne, Chu, Colin J., Copland, David A., Lait, Philippa J. P., Khera, Tarnjit K., Dick, Andrew D., Nicholson, Lindsay B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2014
Materias:	Autoimmunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009498/ https://www.ncbi.nlm.nih.gov/pubmed/24740509 http://dx.doi.org/10.4049/jimmunol.1301390

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