Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival

Somatic missense mutations can initiate tumorogenesis and, conversely, anti-tumor cytotoxic T cell (CTL) responses. Tumor genome analysis has revealed extreme heterogeneity among tumor missense mutation profiles, but their relevance to tumor immunology and patient outcomes has awaited comprehensive...

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Detalles Bibliográficos
Autores principales: Brown, Scott D., Warren, Rene L., Gibb, Ewan A., Martin, Spencer D., Spinelli, John J., Nelson, Brad H., Holt, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009604/
https://www.ncbi.nlm.nih.gov/pubmed/24782321
http://dx.doi.org/10.1101/gr.165985.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009604/
https://www.ncbi.nlm.nih.gov/pubmed/24782321
http://dx.doi.org/10.1101/gr.165985.113

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