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Genome methylation in D. melanogaster is found at specific short motifs and is independent of DNMT2 activity

Cytosine methylation in the genome of Drosophila melanogaster has been elusive and controversial: Its location and function have not been established. We have used a novel and highly sensitive genomewide cytosine methylation assay to detect and map genome methylation in stage 5 Drosophila embryos. T...

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Detalles Bibliográficos
Autores principales: Takayama, Sachiko, Dhahbi, Joseph, Roberts, Adam, Mao, Guanxiong, Heo, Seok-Jin, Pachter, Lior, Martin, David I.K., Boffelli, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009611/
https://www.ncbi.nlm.nih.gov/pubmed/24558263
http://dx.doi.org/10.1101/gr.162412.113