High-Throughput Screen of Natural Product Libraries for Hsp90 Inhibitors

Hsp90 has become the target of intensive investigation, as inhibition of its function has the ability to simultaneously incapacitate proteins that function in pathways that represent the six hallmarks of cancer. While a number of Hsp90 inhibitors have made it into clinical trials, a number of short-...

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Detalles Bibliográficos
Autores principales: Davenport, Jason, Balch, Maurie, Galam, Lakshmi, Girgis, Antwan, Hall, Jessica, Blagg, Brian S. J., Matts, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009755/
https://www.ncbi.nlm.nih.gov/pubmed/24833337
http://dx.doi.org/10.3390/biology3010101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009755/
https://www.ncbi.nlm.nih.gov/pubmed/24833337
http://dx.doi.org/10.3390/biology3010101

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