A Comparison of Two Single-Stranded DNA Binding Models by Mutational Analysis of APOBEC3G

APOBEC3G is the best known of several DNA cytosine deaminases that function to inhibit the replication of parasitic genetic elements including the lentivirus HIV. Several high-resolution structures of the APOBEC3G catalytic domain have been generated, but none reveal how this enzyme binds to substra...

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Detalles Bibliográficos
Autores principales: Shindo, Keisuke, Li, Ming, Gross, Phillip J., Brown, William L., Harjes, Elena, Lu, Yongjian, Matsuo, Hiroshi, Harris, Reuben S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009770/
https://www.ncbi.nlm.nih.gov/pubmed/24832226
http://dx.doi.org/10.3390/biology1020260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009770/
https://www.ncbi.nlm.nih.gov/pubmed/24832226
http://dx.doi.org/10.3390/biology1020260

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