Global Conformational Dynamics of HIV-1 Reverse Transcriptase Bound to Non-Nucleoside Inhibitors

HIV-1 Reverse Transcriptase (RT) is a multifunctional enzyme responsible for the transcription of the RNA genome of the HIV virus into DNA suitable for incorporation within the DNA of human host cells. Its crucial role in the viral life cycle has made it one of the major targets for antiretroviral d...

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Detalles Bibliográficos
Autores principales: Wright, David W., Hall, Benjamin A., Kellam, Paul, Coveney, Peter V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009785/
https://www.ncbi.nlm.nih.gov/pubmed/24832224
http://dx.doi.org/10.3390/biology1020222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009785/
https://www.ncbi.nlm.nih.gov/pubmed/24832224
http://dx.doi.org/10.3390/biology1020222

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