Whole Genome Sequencing and a New Bioinformatics Platform Allow for Rapid Gene Identification in D. melanogaster EMS Screens

Forward genetic screens in Drosophila melanogaster using ethyl methanesulfonate (EMS) mutagenesis are a powerful approach for identifying genes that modulate specific biological processes in an in vivo setting. The mapping of genes that contain randomly-induced point mutations has become more effici...

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Detalles Bibliográficos
Autores principales: Gonzalez, Michael A., Van Booven, Derek, Hulme, William, Ulloa, Rick H., Lebrigio, Rafael F. Acosta, Osterloh, Jeannette, Logan, Mary, Freeman, Marc, Zuchner, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009818/
https://www.ncbi.nlm.nih.gov/pubmed/24832518
http://dx.doi.org/10.3390/biology1030766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009818/
https://www.ncbi.nlm.nih.gov/pubmed/24832518
http://dx.doi.org/10.3390/biology1030766

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