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Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism

Sleep disruption has detrimental effects on glucose metabolism through pathways that remain poorly defined. Although numerous studies have examined the consequences of sleep deprivation (SD) in the brain, few have directly tested its effects on peripheral organs. We examined several tissues in mice...

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Detalles Bibliográficos
Autores principales: Naidoo, Nirinjini, Davis, James G, Zhu, Jingxu, Yabumoto, Maya, Singletary, Kristan, Brown, Marishka, Galante, Raymond, Agarwal, Beamon, Baur, Joseph A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009977/
https://www.ncbi.nlm.nih.gov/pubmed/24102714
http://dx.doi.org/10.1111/acel.12158