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Enzymatic and Structural Characterization of rTSγ Provides Insights into the Function of rTSβ
[Image: see text] In humans, the gene encoding a reverse thymidylate synthase (rTS) is transcribed in the reverse direction of the gene encoding thymidylate synthase (TS) that is involved in DNA biosynthesis. Three isoforms are found: α, β, and γ, with the transcript of the α-isoform overlapping wit...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010280/ https://www.ncbi.nlm.nih.gov/pubmed/24697329 http://dx.doi.org/10.1021/bi500349e |