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Enzymatic and Structural Characterization of rTSγ Provides Insights into the Function of rTSβ

[Image: see text] In humans, the gene encoding a reverse thymidylate synthase (rTS) is transcribed in the reverse direction of the gene encoding thymidylate synthase (TS) that is involved in DNA biosynthesis. Three isoforms are found: α, β, and γ, with the transcript of the α-isoform overlapping wit...

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Detalles Bibliográficos
Autores principales:	Wichelecki, Daniel J., Froese, D. Sean, Kopec, Jolanta, Muniz, Joao R.C., Yue, Wyatt W., Gerlt, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010280/ https://www.ncbi.nlm.nih.gov/pubmed/24697329 http://dx.doi.org/10.1021/bi500349e

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