Voacamine Modulates the Sensitivity to Doxorubicin of Resistant Osteosarcoma and Melanoma Cells and Does Not Induce Toxicity in Normal Fibroblasts

[Image: see text] In previous studies it has been demonstrated that the plant alkaloid voacamine (1), used at noncytotoxic concentrations, enhanced the cytotoxicity of doxorubicin and exerted a chemosensitizing effect on cultured multidrug-resistant (MDR) U-2 OS-DX osteosarcoma cells. The in vitro i...

Descripción completa

Detalles Bibliográficos
Autores principales: Condello, Maria, Cosentino, Dario, Corinti, Silvia, Di Felice, Gabriella, Multari, Giuseppina, Gallo, Francesca Romana, Arancia, Giuseppe, Meschini, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010292/
https://www.ncbi.nlm.nih.gov/pubmed/24720452
http://dx.doi.org/10.1021/np400950h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010292/
https://www.ncbi.nlm.nih.gov/pubmed/24720452
http://dx.doi.org/10.1021/np400950h

Ejemplares similares