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Structure and Dynamics of a Fusion Peptide Helical Hairpin on the Membrane Surface: Comparison of Molecular Simulations and NMR

[Image: see text] The conserved N-terminal residues of the HA2 subunit of influenza hemagglutinin (fusion peptide) are essential for membrane fusion and viral entry. Recent NMR studies showed that the 23-residue fusion peptide forms a helical hairpin that undergoes rocking motion relative to the mem...

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Detalles Bibliográficos
Autores principales: Brice, Allyn R., Lazaridis, Themis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010296/
https://www.ncbi.nlm.nih.gov/pubmed/24712538
http://dx.doi.org/10.1021/jp409412g