Antineoplastic Agents. 595. Structural Modifications of Betulin and the X-ray Crystal Structure of an Unusual Betulin Amine Dimer1

[Image: see text] The lupane-type triterpene betulin (1) has been subjected to a series of structural modifications for the purpose of evaluating resultant cancer cell growth inhibitory activity. The reaction sequence 7 → 11 → 12 was especially noteworthy in providing a betulin-derived amine dimer....

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Detalles Bibliográficos
Autores principales: Pettit, George R., Melody, Noeleen, Hempenstall, Frank, Chapuis, Jean-Charles, Groy, Thomas L., Williams, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010298/
https://www.ncbi.nlm.nih.gov/pubmed/24694263
http://dx.doi.org/10.1021/np400947d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010298/
https://www.ncbi.nlm.nih.gov/pubmed/24694263
http://dx.doi.org/10.1021/np400947d

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